Letter: Essential thrombocythaemia, polycythaemia, and peripheral gangrene.
نویسندگان
چکیده
منابع مشابه
Peripheral gangrene in polycythaemia vera.
well account for the phonocardiographic features of extreme variability of the A2-OC interval and the intermittent absence of the OC. The systolic murmur was in keeping with mitral reflux with its rate related variability. In a very ill patient with a malfunctioning mitral Starr-Edwards prosthesis we feel that the phonocardiographic findings can be a useful bedside adjunct to the physician and ...
متن کاملAntiplatelet drugs for polycythaemia vera and essential thrombocythaemia.
BACKGROUND Polycythaemia vera and essential thrombocythaemia are chronic Philadelphia-negative myeloproliferative disorders, which increase the risk of arterial and venous thrombosis as well as bleeding. In addition to the different therapeutic strategies available, aspirin is often used to prevent platelet aggregation. OBJECTIVES To quantify the benefit and harm of antiplatelet drugs for lon...
متن کاملThrombosis and haemorrhage in polycythaemia vera and essential thrombocythaemia.
Despite decades of clinical and laboratory research, relatively little has been accomplished concerning the pathogenesis as well as the identification of risk factors for thrombosis and bleeding in myeloproliferative disorders. In polycythaemia vera, the pro-thrombotic effect of an elevated haematocrit is well established. In contrast, thrombocytosis per se has not been similarly incriminated i...
متن کاملMasked polycythaemia vera is genetically intermediate between JAK2V617F mutated essential thrombocythaemia and overt polycythaemia vera
Polycythaemia vera (PV) can be defined as a myeloproliferative neoplasm (MPN) with erythrocytosis and JAK2V617F (or an equivalent marker of clonality). While these simple criteria are sufficient for most cases of overt PV, an estimated 10–15% of PV patients do not have an elevated haemoglobin concentration (Hb) and may mimic JAK2-positive essential thrombocythaemia (ET). This poses a problem fo...
متن کاملHeadache in essential thrombocythaemia
Headache is frequently reported as one of the neurological manifestations of essential thrombocythaemia (ET) and other myeloproliferative neoplasms. It is associated with considerable morbidity; yet, it is a frequently under-recognised symptom. In patients with ET, headaches may be attributable to the disease, to the prescribed ET treatment, or unrelated to ET. The majority of headaches in ET a...
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ژورنال
عنوان ژورنال: BMJ
سال: 1975
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5956.515-a